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Endocrine Abstracts

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ea0065p182 | Metabolism and Obesity | SFEBES2019

Oral chenodeoxycholic acid increases post-prandial anorectic gut hormone levels and increases indices of insulin sensitivity

McGlone Emma Rose , Malallah Khalefah , Bloom Stephen , Tan Tricia

Background: Increased circulating bile acids may contribute to improved glucose control and augmented secretion of the gut hormones peptide tyrosine tyrosine (PYY) and glucagon-like peptide-1 (GLP-1) observed post-prandially in patients following bariatric surgery. Oral bile acids could represent a non-surgical means of improving glucose tolerance after a meal.Aim: To investigate the effects of a single oral dose of ursodeoxycholic acid (UDCA) and chenod...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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